Computed tomographic colonography (CTC); colorectal cancer diagnosis with CTC in an Auckland population

J Med Imaging Radiat Oncol. 2013 Oct;57(5):572-5. doi: 10.1111/1754-9485.12062. Epub 2013 May 21.

Abstract

Aim: To determine the sensitivity of computed tomographic colonography (CTC) in the detection of colorectal cancer in our population and evaluate the reasons why these lesions may be missed on CTC.

Methods: All patients who underwent CTC in the 65-month period from 1 January 2004 to 1 July 2009 were included in the analysis. Demographic data and CTC findings were recorded, according to the CT Colonography Reporting and Data System. Data were cross-matched with the National Cancer Registry results for colorectal cancer cases between 1 January 2004 and 1 October 2009, 3 months longer to include any delayed diagnoses.

Results: There were 2026 consecutive CTC patients, comprising 52.6% female, average age of 60 years; range 19-87. Approximately 84% were symptomatic. There were 45 confirmed colorectal cancers among this patient group in the National Cancer Registry during the relevant time period compared with 43 suspected cancers on CTC, giving a miss rate of 2 of 45, or 4.4%.

Conclusion: The sensitivity of 95% for CTC in the detection of colorectal cancer compares favourably with the published national and international data.

Keywords: body CT; gastrointestinal imaging; quality assurance.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Colonography, Computed Tomographic / statistics & numerical data*
  • Colorectal Neoplasms / diagnostic imaging*
  • Colorectal Neoplasms / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • New Zealand / epidemiology
  • Observer Variation
  • Prevalence
  • Registries*
  • Reproducibility of Results
  • Risk Factors
  • Sensitivity and Specificity
  • Young Adult