Neurogenic [corrected] and oropharyngeal dysphagia

Ann N Y Acad Sci. 2013 Oct:1300:1-10. doi: 10.1111/nyas.12234.

Abstract

Oropharyngeal dysphagia (OD) is a swallowing disorder caused by congenital abnormalities and structural damage and disease-associated damage of the oral cavity, pharynx, and upper esophageal sphincter. Patients with OD lack the protective mechanisms necessary for effective swallowing, exhibiting difficulty controlling food in the mouth and initiating a swallow, leading to choking, coughing, and nasal regurgitation. OD is a major risk factor for malnutrition, dehydration, and aspiration pneumonia. The following on OD includes commentaries on the application of simulation of oropharyngeal transient receptor potential vanilloid 1 (TRPV1) and maneuvers like the Shaker exercise to improve the safety and efficacy of swallow in OD patients; the prevalence of esophageal pathologies in OD patients and the need to evaluate the esophagus, esophagogastric junction, and stomach; and strategies for clinical screening to detect OD and aspiration among high-risk patients and to improve oral health care, maintain nutrition and hydration, and prevent aspiration pneumonia.

Keywords: FEES; TRPV1; oral health care; oropharyngeal dysphagia; swallow.

Publication types

  • Review

MeSH terms

  • Deglutition / physiology*
  • Deglutition Disorders / epidemiology
  • Deglutition Disorders / etiology
  • Deglutition Disorders / physiopathology*
  • Humans
  • Nutritional Status
  • Oropharynx / physiopathology*
  • Prevalence
  • Risk Factors
  • TRPV Cation Channels / physiology

Substances

  • TRPV Cation Channels
  • TRPV1 protein, human