[Association between multiple myeloma and acute myeloid leukemia secondary to myelodysplastic syndrome]

Selim Jennane; Hicham Eddou; El Mehdi Mahtat; Johanna Konopacki; Bertrand Souleau; Jean Valère Malfuson; Vincent Foissaud; Thierry de Revel

doi:10.1684/abc.2013.0880

[Association between multiple myeloma and acute myeloid leukemia secondary to myelodysplastic syndrome]

Ann Biol Clin (Paris). 2013 Sep-Oct;71(5):581-4. doi: 10.1684/abc.2013.0880.

[Article in French]

Authors

Selim Jennane¹, Hicham Eddou, El Mehdi Mahtat, Johanna Konopacki, Bertrand Souleau, Jean Valère Malfuson, Vincent Foissaud, Thierry de Revel

Affiliation

¹ Service d'hématologie clinique, Hôpital militaire d'instruction Mohammed V, Rabat, Maroc.

PMID: 24113443
DOI: 10.1684/abc.2013.0880

Abstract

We report a rare case of association of two distinct hematologic malignancies: refractory cytopenia with multilineage dysplasia associated with del(5q) and symptomatic multiple myeloma associated with del(17p) and del(13q). After 16 months, the patient presented an acute leukemic transformation of the myelodysplasic syndrome.

Keywords: acute myeloblastic leukemia; multiple myeloma; myelodysplastic syndrome.

Publication types

Case Reports
English Abstract

MeSH terms

Aged
Cell Transformation, Neoplastic / genetics
Fatal Outcome
Humans
Leukemia, Myeloid, Acute / complications*
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / genetics
Male
Multiple Myeloma / complications*
Multiple Myeloma / diagnosis
Myelodysplastic Syndromes / complications*
Myelodysplastic Syndromes / diagnosis
Myelodysplastic Syndromes / genetics