Local chemotherapeutic agents for the treatment of ocular malignancies

Bruno F Fernandes; Katerina Nikolitch; James Coates; Gustavo Novais; Alexandre Odashiro; Patricia P Odashiro; Rubens N Belfort; Miguel N Burnier Jr

doi:10.1016/j.survophthal.2013.01.003

Local chemotherapeutic agents for the treatment of ocular malignancies

Surv Ophthalmol. 2014 Jan-Feb;59(1):97-114. doi: 10.1016/j.survophthal.2013.01.003. Epub 2013 Oct 8.

Authors

Bruno F Fernandes¹, Katerina Nikolitch², James Coates², Gustavo Novais², Alexandre Odashiro², Patricia P Odashiro², Rubens N Belfort², Miguel N Burnier Jr²

Affiliations

¹ Department of Ophthalmology and Pathology, The McGill University Health Center, and Henry C. Witelson Ocular Pathology Laboratory, Montreal, Canada. Electronic address: bruno.mtl@gmail.com.
² Department of Ophthalmology and Pathology, The McGill University Health Center, and Henry C. Witelson Ocular Pathology Laboratory, Montreal, Canada.

PMID: 24112549
DOI: 10.1016/j.survophthal.2013.01.003

Abstract

We critically analyze available peer-reviewed literature, including clinical trials and case reports, on local ocular cancer treatments. Recent innovations in many areas of ocular oncology have introduced promising new therapies, but, for the most part, the optimal treatment of ocular malignancies remains elusive.

Keywords: CIN; PAM; carboplatin; carcinoma; conjunctiva; interferon; melanoma; mytomicin; retinoblastoma.

Publication types

Review

MeSH terms

Animals
Antineoplastic Agents / therapeutic use*
Carcinoma in Situ / drug therapy*
Conjunctival Neoplasms / drug therapy*
Corneal Diseases / drug therapy*
Humans
Lymphoma / drug therapy*
Retinal Neoplasms / drug therapy*
Retinoblastoma / drug therapy*

Substances

Antineoplastic Agents