Approaching the limit: can one DNA strand assemble into defined nanostructures?

Langmuir. 2014 May 27;30(20):5859-62. doi: 10.1021/la402326b. Epub 2013 Oct 18.

Abstract

This article reports a simple, symmetrical DNA building block (motif): a bulged DNA duplex consisting of two short, identical strands. Multiple copies of the same motif can interact with each other through T junctions. The resulting superstructures include predesigned 1D and 2D arrays that have been visualized by atomic force microscopy (AFM).

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • DNA / chemistry*
  • Microscopy, Atomic Force
  • Nanostructures / chemistry*
  • Oligonucleotides / chemistry*

Substances

  • Oligonucleotides
  • DNA