An assessment of outcomes in 187 patients with ST elevation myocardial infarction (STEMI) with multivessel coronary disease who underwent primary percutaneous coronary intervention (PCI) was done. All patients were divided into two groups: in group 1 (n=39) second phase of revasculrization was performed within 60 days, in group 2 (n=148) it was carried out or planned in more than 60 days after index event. During 12 months of follow up rates of combined end point (death, myocardial infarction, target vessel revascularization [TVR]) and TVR in group 1 were lower than in group 2 (5.1 vs 27.7%, and 0 vs 11.5%, respectivelly, p=0.05). We also observed tendency to lower reinfarction rate in group 1 (0 vs 9.46%, p=0.09). There was no significant difference between groups in number of deaths (5.1% vs 6.7%, respectively).