Abstract
We report here the interesting case of a 76-year-old man with severe proteinuria who was diagnosed with systemic mastocytosis accompanied by a clonal non-mast-cell lineage haematological disorder (a non-secretory plasma cell dyscrasia). This is a unique report of systemic mastocytosis with a non-secretory plasma cell dyscrasia and nephrotic syndrome. The pathophysiological relevance between these entities along with the probability of occult amyloidosis is discussed.
Copyright © 2013 S. Karger AG, Basel.
MeSH terms
-
Aged
-
Amyloidosis / diagnosis
-
Anemia / drug therapy
-
Anemia / etiology
-
Biopsy
-
Bone Marrow / pathology
-
Clone Cells / pathology
-
Coloring Agents
-
Congo Red
-
Darbepoetin alfa
-
Drug Therapy, Combination
-
Erythropoietin / analogs & derivatives
-
Erythropoietin / therapeutic use
-
Factor X Deficiency / complications
-
Gingiva / pathology
-
Hemorrhagic Disorders / etiology
-
Histamine Antagonists / therapeutic use
-
Humans
-
Male
-
Mastocytosis, Systemic / complications*
-
Mastocytosis, Systemic / drug therapy
-
Nephrotic Syndrome / etiology*
-
Paraproteinemias / complications*
-
Prednisone / therapeutic use
-
Proteinuria / etiology*
-
Splenectomy
-
Splenomegaly / etiology
-
Subcutaneous Fat / pathology
Substances
-
Coloring Agents
-
Histamine Antagonists
-
Erythropoietin
-
Darbepoetin alfa
-
Congo Red
-
Prednisone