In 1888, the Canadian Presbyterian Church went to northern Henan as "medical missionary", and established the Boji Hospital in Weihui in 1903. The Hospital was expanded in size in another site with its name changed to Huimin Hospital in 1923. For satisfying the demand of increasing patients, and creating the Care and Management System for hospital and medical treatment, the General Nursing School of Huimin Hospital was established, emphasizing a new nursing system for a clean, comfortable, bright, quiet and orderly environment, paying more attention to practice-oriented teaching method. It opened a modern nursing culture with characteristics of northern Henan, and provided referential experience to medical education in northern Henan, which had a positive influence on localization of Western medicine.