Optical and visual simulation of standard and modified spherical aberration implantable Collamer lens post myopic LASIK surgery

Eur J Ophthalmol. 2014 May-Jun;24(3):330-7. doi: 10.5301/ejo.5000372. Epub 2013 Sep 19.

Abstract

Purpose: To evaluate the visual quality achieved in patients undergoing standard or modified implantable Collamer lens (ICL) to correct residual myopic error after laser-assisted in situ keratomileusis (LASIK) surgery.

Methods: The adaptive optics visual simulator was used to simulate LASIK surgery of moderate and high myopia with a myopic regression corrected by a standard and modified ICL. Visual acuity (VA) and contrast sensitivity (CS) were measured in 14 subjects at 3- and 4.5-mm pupil. Point spread function and simulated retinal images were calculated.

Results: Comparing LASIK plus standard ICL and LASIK plus modified ICL simulations, for moderate myopia, VA improvement was less than 1 line in all VA contrasts and both pupils evaluated. No statistically significant differences were found in CS between the simulations at any spatial frequency evaluated and for 3-mm pupil (p>0.05), but differences were significant at 4.5-mm pupil (p<0.05). For high myopia, the VA improvement was less than 1 line at 3-mm pupil, although it increased 2 or more lines at 4.5-mm pupil. Statistically significant differences were found in CS between the simulations for all spatial frequencies and both pupils evaluated (p<0.05), except for low and medium spatial frequencies at 3-mm pupil (p>0.05).

Conclusions: These outcomes suggest that an ICL is a good option to correct the myopic residual error after myopic LASIK. When the ICL's spherical aberration is modified, the post-LASIK eyes of high myopia are the most benefited, as these eyes are more aberrated than after moderate myopic LASIK.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aberrometry
  • Adolescent
  • Adult
  • Contrast Sensitivity
  • Corneal Wavefront Aberration / physiopathology*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / methods*
  • Lasers, Excimer / therapeutic use*
  • Lens Implantation, Intraocular / methods*
  • Male
  • Myopia / physiopathology
  • Myopia / surgery*
  • Optics and Photonics
  • Phakic Intraocular Lenses*
  • Postoperative Period
  • Visual Acuity / physiology
  • Young Adult