In the universe all the creatures are related to Adhivyadhi, which indicates mental agony or bodily pain. Acharyas of Ayurveda like Charaka, Sushruta and Kashyap have classified diseases into various categories like Agantuja, Sharirika, Manasika, Swabhavika, etc. Charaka classified diseases based on the prognosis like Sadhya, Asadhya, Mrudu and Daruna. Ayurveda also suggested Daiva Vyapashraya Chikitsa which includes of Manidharana and chanting Mantras. Astrological sciences suggest 10 types of remedial measures in the treatment of diseases. This science considers that causative factors of various disorders are the Navagrahas (nine planets). The influence of the planets on various procedures like drug processing, bath taking, performing Yajna, wearing Ratna, etc. are well documented in Jyotishashastra. Drugs processed in Chandra Nakshatra acts as ambrosia and subdues Tridoshajanya Vyadhi. Medicated baths are suggested for diseases engendered due to involvement of different planet effects viz. Sarshpa for Shukra, Haridra and Daruharidra for Shani Lodhra for Ketu, Sharpunkha for Rahu, etc. In a close scrutiny it appears that Jyotishashastra Siddhanta can play crucial role in the management of chronic diseases.