miREval 2.0: a web tool for simple microRNA prediction in genome sequences

Dadi Gao; Robert Middleton; John E J Rasko; William Ritchie

doi:10.1093/bioinformatics/btt545

miREval 2.0: a web tool for simple microRNA prediction in genome sequences

Bioinformatics. 2013 Dec 15;29(24):3225-6. doi: 10.1093/bioinformatics/btt545. Epub 2013 Sep 18.

Authors

Dadi Gao¹, Robert Middleton, John E J Rasko, William Ritchie

Affiliation

¹ Bioinformatics Laboratory, Centenary Institute, Gene and Stem Cell Therapy Program, Centenary Institute, University of Sydney, Sydney, New South Wales, Australia and Cell and Molecular Therapies, Royal Prince Alfred Hospital, Camperdown, New South Wales 2050, Australia.

Abstract

Result: We have developed miREval 2.0, an online tool that can simultaneously search up to 100 sequences for novel microRNAs (miRNAs) in multiple organisms. miREval 2.0 uses multiple published in silico approaches to detect miRNAs in sequences of interest. This tool can be used to discover miRNAs from DNA sequences or to validate candidates from sequencing data.

Availability: http://mimirna.centenary.org.au/mireval/.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Genome*
Internet*
MicroRNAs / genetics*
Sequence Analysis, RNA / methods*
Software*
Support Vector Machine

Substances

MicroRNAs

Grants and funding

571156/Medical Research Council/United Kingdom