The worldwide epidemiology of melioidosis is changing. We describe a case of acute melioidosis in Spain in a patient who had traveled to Africa. A novel sequence type of Burkholderia pseudomallei was identified in this patient. Clinicians should be aware of the possibility of melioidosis in travelers returning from melioidosis-nonendemic regions.
Keywords: Africa; Burkholderia pseudomallei; Spain; bacteria; global health; gram-negative; melioidosis; travel; travel-related infections; traveler.