Acquired resistance to crizotinib from a mutation in CD74-ROS1

N Engl J Med. 2013 Sep 19;369(12):1173. doi: 10.1056/NEJMc1309091.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Adenocarcinoma / genetics*
  • Drug Resistance / genetics*
  • Female
  • Humans
  • Lung Neoplasms / genetics*
  • Protein Kinase Inhibitors / therapeutic use*
  • Protein-Tyrosine Kinases / genetics*
  • Proto-Oncogene Proteins / genetics*
  • Pyrazoles / therapeutic use*
  • Pyridines / therapeutic use*
  • Translocation, Genetic*

Substances

  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins
  • Pyrazoles
  • Pyridines
  • Protein-Tyrosine Kinases