Abstract
We herein report the case of a 17-year-old man who developed an increased plasma creatinine level (11.1 mg/dL) and oliguria with massive proteinuria (27.3 g/day) four weeks after an abraded wound to his right knee. The histology of the renal biopsy specimens showed diffuse endocapillary proliferative glomerulonephritis with the deposition of nephritis-associated plasmin receptor in the glomerulus. A case of acute kidney injury due to nephrotic syndrome caused by acute post-streptococcal glomerulonephritis was diagnosed. His renal function and proteinuria were improved with supportive care, including hemodialysis, without the administration of immunosuppressive agents.
MeSH terms
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Acute Kidney Injury / etiology*
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Acute Kidney Injury / immunology
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Acute Kidney Injury / microbiology
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Adolescent
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Antigens, Bacterial / metabolism*
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Glomerulonephritis / etiology*
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Glomerulonephritis / immunology
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Glomerulonephritis / microbiology
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Humans
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Kidney Glomerulus / immunology
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Kidney Glomerulus / microbiology
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Kidney Glomerulus / pathology
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Male
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Nephrotic Syndrome / etiology*
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Nephrotic Syndrome / immunology
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Nephrotic Syndrome / microbiology
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Receptors, Cell Surface / metabolism*
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Streptococcal Infections / complications*
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Streptococcal Infections / immunology
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Streptococcal Infections / microbiology
Substances
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Antigens, Bacterial
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Receptors, Cell Surface
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nephritis-associated plasminogen receptor, Streptococcus