Large embolus in transit - an unresolved therapeutic dilemma (case report and review of literature)

Heart Lung. 2014 Mar-Apr;43(2):152-4. doi: 10.1016/j.hrtlng.2013.08.005. Epub 2013 Sep 14.

Abstract

Floating right heart thrombus, also known as "emboli in transit" is a potentially fatal condition, of varying etiology and usually coexisting with massive pulmonary embolism. Although the mortality rate is as high as 40%, there are no established therapeutic guidelines. A case is presented of an 84 year old female with a history of colon cancer and coronary artery disease who presented with sudden onset unresponsiveness. She was intubated in the ED and started on intravenous pressor support. A free floating large right ventricular thrombus and dilated right ventricle were noted on transthoracic echocardiogram (TTE). She was managed medically with good short term outcome. Floating right heart thrombus is a rare occurrence. Recognition of signs and symptoms along with early TTE is critical for diagnosis and consideration of treatment modality. The existing literature does not offer a clear consensus for management of pulmonary embolism with co-existing mobile intra-cardiac thrombus. Choice of treatment is crucial and should be considered on a case-by-case basis after careful assessment of indications, contraindications, risks and benefits.

Keywords: Critical care; Right heart thrombus; Thrombolytic therapy; Transthoracic echocardiography.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Echocardiography
  • Female
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / drug therapy*
  • Heart Diseases / surgery
  • Humans
  • Thrombolytic Therapy*
  • Thrombosis / diagnostic imaging
  • Thrombosis / drug therapy*
  • Thrombosis / surgery