Clonal seborrheic keratosis: dermoscopic and confocal microscopy characterization

J Eur Acad Dermatol Venereol. 2014 Oct;28(10):1397-400. doi: 10.1111/jdv.12261. Epub 2013 Sep 4.

Abstract

Background: The diagnosis of clonal seborrheic keratosis may be challenging clinically and histologically.

Objective: In our study, we describe the common aspects of this benign entity that show peculiar dermoscopic and confocal findings.

Methods: A total of nine clonal seborrheic keratosis were analyzed.

Results: Upon dermoscopy, it reveals the presence of globular-like structures and sharply demarcated borders whereas confocal microscopy displays the typical intraepidermal nesting of pigmented keratinocytes that permits to have a reliable in vivo diagnosis.

Conclusions: Dermoscopy and confocal microscopy permit to in vivo diagnose this variant of seborrheic keratosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dermoscopy / methods*
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • Humans
  • Keratosis, Seborrheic / diagnosis*
  • Male
  • Microscopy, Confocal / methods*
  • Middle Aged
  • Reproducibility of Results
  • Retrospective Studies