The clinical burden and predictors of sequelae following invasive meningococcal disease in Australian children

Pediatr Infect Dis J. 2014 Mar;33(3):316-8. doi: 10.1097/INF.0000000000000043.

Abstract

Of 109 children admitted to a tertiary paediatric hospital with a diagnosis of invasive meningococcal disease from 2000-2011, 37.6% (n = 41) developed sequelae; for serogroup B, 41.3% developed sequelae. Independent predictors of sequelae included: fever ≥ 39 °C on hospital presentation [odds ratio (OR): 4.5; P = 0.012] and a diagnosis of septicemia with meningitis compared with septicemia alone (OR: 15.5; P < 0.001) and meningitis alone (OR: 7.8; P = 0.002).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Australia / epidemiology
  • Child
  • Child, Preschool
  • Female
  • Fever
  • Humans
  • Hypotension
  • Infant
  • Infant, Newborn
  • Male
  • Meningitis, Meningococcal
  • Meningococcal Infections / complications*
  • Meningococcal Infections / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Sepsis