Solitary fibrous tumors of the kidneys: presentation, evaluation, and treatment

Urol Int. 2013;91(4):373-83. doi: 10.1159/000354394. Epub 2013 Aug 29.

Abstract

Introduction: Renal solitary fibrous tumors (SFTs) are spindle cell neoplasms of mesenchymal origin, and very rare with only 46 cases reported worldwide to date. It is crucial to differentiate this tumor from other tumors of the kidney, so as to avoid unnecessary treatment. Therefore, our objective was to review reports of renal SFTs, their clinical presentations, imaging methods, and surgical management, updated to 2013.

Material and methods: We retrospectively reviewed articles published in the USA, Europe, and Asia from 1996 to date using PubMed, Medscape, Medline, and several major journals. We report on areas of controversy and well-established guidelines.

Results: We reviewed 58 articles which confirmed, with a high level of evidence-based medicine, that the male-to-female ratio is equal and their most common presentation is an incidental finding on a radiological study, in which it is difficult to differentiate them from renal cell carcinoma. Nephrectomy is the gold standard treatment, with almost no recurrence.

Conclusions: In symptomatic patients, complete surgical resection of renal SFTs may provide a very good outcome, with almost no recurrence.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Renal Cell / diagnosis
  • Diagnosis, Differential
  • Female
  • Humans
  • Kidney / pathology
  • Kidney / surgery
  • Kidney Neoplasms / diagnosis*
  • Kidney Neoplasms / surgery
  • Kidney Neoplasms / therapy*
  • Male
  • Middle Aged
  • Nephrectomy
  • Solitary Fibrous Tumors / diagnosis*
  • Solitary Fibrous Tumors / surgery
  • Solitary Fibrous Tumors / therapy*
  • Treatment Outcome