Versatile antibody-sensing Boolean logic for the simultaneous detection of multiple bacterial toxins

Chem Commun (Camb). 2013 Oct 18;49(81):9314-6. doi: 10.1039/c3cc45370g.

Abstract

We present an OR gate based on monoclonal antibodies for the simultaneous detection of multiple toxins in a single tube. To further simplify the operating procedure, the Boolean rule of simplification was used to guide the selection of a marker toxin among the natural toxin profiles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal / immunology*
  • Bacillus cereus / metabolism
  • Bacterial Toxins / analysis*
  • Bacterial Toxins / immunology
  • Enzyme-Linked Immunosorbent Assay*
  • Humans

Substances

  • Antibodies, Monoclonal
  • Bacterial Toxins