Diagnosis and management of infection in the diabetic foot

Med Clin North Am. 2013 Sep;97(5):911-46. doi: 10.1016/j.mcna.2013.04.005. Epub 2013 Jun 5.

Abstract

Foot infections are common in persons with diabetes mellitus. Most diabetic foot infections occur in a foot ulcer, which serves as a point of entry for pathogens. Unchecked, infection can spread contiguously to involve underlying tissues, including bone. A diabetic foot infection is often the pivotal event leading to lower extremity amputation, which account for about 60% of all amputations in developed countries. Given the crucial role infections play in the cascade toward amputation, all clinicians who see diabetic patients should have at least a basic understanding of how to diagnose and treat this problem.

Keywords: Antibiotic therapy; Culture techniques; Diabetic foot; Foot infection; Microbiology; Osteomyelitis.

Publication types

  • Review

MeSH terms

  • Amputation, Surgical
  • Anti-Bacterial Agents / therapeutic use
  • Arthropathy, Neurogenic / complications
  • Arthropathy, Neurogenic / diagnosis*
  • Arthropathy, Neurogenic / surgery
  • Arthropathy, Neurogenic / therapy*
  • Diabetic Foot / complications
  • Diabetic Foot / diagnosis*
  • Diabetic Foot / therapy*
  • Humans
  • Limb Salvage
  • Osteomyelitis / complications
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / therapy*
  • Secondary Prevention
  • Severity of Illness Index
  • Wound Healing / physiology

Substances

  • Anti-Bacterial Agents