Abstract
Powers and Trobridge examine the impact of fetal bovine serum (FBS) on viral vector production. They demonstrate that there can be significant variability between different FBS production lots in the resultant viral titer of both foamy and lentivirus vectors.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Cattle
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Culture Media, Serum-Free / pharmacology*
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Genetic Vectors
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HEK293 Cells
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Humans
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Lentivirus / drug effects
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Lentivirus / genetics
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Lentivirus / growth & development*
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Spumavirus / drug effects
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Spumavirus / genetics
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Spumavirus / growth & development*
Substances
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Culture Media, Serum-Free