Tapia's syndrome secondary to laterocervical localization of diffuse large cell lymphoma

Brain Dev. 2014 Jun;36(6):548-50. doi: 10.1016/j.braindev.2013.07.008. Epub 2013 Aug 16.

Abstract

The eponym "Tapia's syndrome" indicates an associated unilateral vocal cord and tongue paralysis secondary to a peripheral involvement of the recurrent laryngeal branch and the hypoglossal nerve. Although mainly observed as a complication of surgery or anaesthesia, it can rarely occur secondary to infectious or neoplastic causes. We are presenting a case of a teen-ager with Tapia's syndrome who had been seeking medical assistance for episodes of loss of consciousness and was diagnosed with a high-grade peripheral B-cell lymphoma, an association not previously described. This syndrome should be remembered even outside the surgical contest for its highly localising value.

Keywords: Cranial nerve palsies; Diffuse large cell lymphoma; Hypoglossal nerve; Recurrent laryngeal nerve.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Diagnosis, Differential
  • Head / pathology
  • Head and Neck Neoplasms / complications*
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / drug therapy
  • Head and Neck Neoplasms / pathology
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / complications*
  • Lymphoma, Large B-Cell, Diffuse / diagnosis
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Magnetic Resonance Imaging
  • Male
  • Neck / pathology
  • Tongue Diseases / diagnosis
  • Tongue Diseases / etiology*
  • Tongue Diseases / pathology
  • Vocal Cord Paralysis / diagnosis
  • Vocal Cord Paralysis / etiology*
  • Vocal Cord Paralysis / pathology