Dipyrone (metamizole) can nullify the antiplatelet effect of aspirin in patients with coronary artery disease

J Am Coll Cardiol. 2013 Oct 29;62(18):1725-1726. doi: 10.1016/j.jacc.2013.07.039. Epub 2013 Aug 14.
No abstract available

Keywords: aspirin; coronary artery disease; dipyrone; high treatment-platelet reactivity; metamizole; nonresponder.

Publication types

  • Letter

MeSH terms

  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Aspirin / therapeutic use*
  • Coronary Artery Disease / drug therapy*
  • Dipyrone / adverse effects*
  • Drug Interactions
  • Humans
  • Platelet Aggregation / drug effects
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Thromboxanes / biosynthesis

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Platelet Aggregation Inhibitors
  • Thromboxanes
  • Dipyrone
  • Aspirin