[Fluid overload and arterial hypertension in hemodialysis patients]

Nephrol Ther. 2013 Nov;9(6):408-15. doi: 10.1016/j.nephro.2013.04.004. Epub 2013 Aug 15.
[Article in French]

Abstract

The water sodium overload is a factor of morbi-mortality and its treatment is one of the markers of adequacy of the hemodialysis treatment. Its first clinical assessment was improved by tools such as echocardiography and ultrasonography of the inferior vena cava, the per-dialytic curve of plasma volume, measuring BNP or proBNP and by impedancemetry. The combination of the evaluation of these parameters and of the clinical situation allows one to assess the extracellular overload, the state of the blood volume and the potential of plasma refilling. The latter is a key factor of the per-dialytic hemodynamic tolerance. It is itself a determining factor in weight can be achieved at the end of the session. Getting the "dry" weight can require modifications of the prescriptions of the hemodialysis sessions, a filling by albumin even a drugs support. Finally, the overload treatment is the central part of the treatment of arterial hypertension, which has to benefit however often from antihypertensive treatment the profit of which is demonstrated.

Keywords: Antihypertensive treatment; Arterial hypertension; BNP; Brain natriuretic peptid; Courbe de volume plasmatique; Hemodialysis; Hypertension artérielle; Hémodialyse; Impedancemetry; Impédancemétrie; Plasma volume curve; Surcharge hydrosodée; Traitement antihypertenseur; Water sodium overload.

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Biomarkers / metabolism
  • Body Water / metabolism*
  • Echocardiography
  • Electric Impedance
  • Fluid Shifts / physiology
  • Hemodynamics / physiology
  • Humans
  • Hypertension / physiopathology
  • Hypertension / therapy*
  • Natriuretic Peptide, Brain / metabolism
  • Peptide Fragments / metabolism
  • Plasma Volume / physiology
  • Renal Dialysis / methods*
  • Vena Cava, Inferior / diagnostic imaging

Substances

  • Antihypertensive Agents
  • Biomarkers
  • Peptide Fragments
  • pro-brain natriuretic peptide (1-76)
  • Natriuretic Peptide, Brain