Light induced DNA-protein conjugation

Chem Commun (Camb). 2013 Oct 7;49(77):8626-8. doi: 10.1039/c3cc43291b.

Abstract

DNA was modified with a photo-reactive caged diene allowing for the modification of dienophile containing proteins under mild irradiation conditions to afford fully functional DNA-protein conjugates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • DNA / chemistry*
  • Immobilized Proteins / chemistry*
  • Light
  • Maleimides / chemistry
  • Models, Molecular
  • Myoglobin / chemistry
  • Proteins / chemistry*

Substances

  • Alkenes
  • Immobilized Proteins
  • Maleimides
  • Myoglobin
  • Proteins
  • maleimide
  • DNA