Fifteen families with clustering of infective dermatitis associated with HTLV-1 (IDH) and/or HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) were observed among 28 families of IDH index cases, 93% of them occurring in two generations. With the exception of two mothers of children with IDH, all the mothers with HAM/TSP had at least one child with HAM/TSP. This is the first report of such clustering involving many families.
Keywords: Clustering of HTLV-1-associated diseases; HTLV-1 associated myelopathy/tropical spastic paraparesis; HTLV-1 infection; HTLV-1 vertical transmission; Infective dermatitis associated with HTLV-1.
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