A case of mild pulmonary disease due to Mycobacterium shimoidei with a favorable outcome

J Clin Microbiol. 2013 Oct;51(10):3467-8. doi: 10.1128/JCM.01028-13. Epub 2013 Aug 7.

Abstract

We describe a case of mild Mycobacterium shimoidei disease with a favorable course after treatment. Characteristics of nine M. shimoidei isolates in Italy between 1989 and 2009 were also reviewed. The M. shimoidei genome was highly conserved. Based on antimicrobial susceptibility, the combination of ethambutol, clarithromycin, and rifabutin appears to be a reasonable treatment.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA-Directed RNA Polymerases / genetics
  • Female
  • Humans
  • Italy
  • Microbial Sensitivity Tests
  • Middle Aged
  • Molecular Sequence Data
  • Mycobacterium / drug effects
  • Mycobacterium / isolation & purification*
  • Mycobacterium Infections / diagnosis*
  • Mycobacterium Infections / drug therapy
  • Mycobacterium Infections / microbiology
  • Mycobacterium Infections / pathology*
  • Pneumonia, Bacterial / diagnosis*
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / microbiology
  • Pneumonia, Bacterial / pathology*
  • Sequence Analysis, DNA
  • Treatment Outcome

Substances

  • Anti-Infective Agents
  • DNA, Bacterial
  • DNA-Directed RNA Polymerases
  • RNA polymerase beta subunit

Associated data

  • GENBANK/HM807416