Metabolic surgery: quo vadis?

Endocrinol Nutr. 2014 Jan;61(1):35-46. doi: 10.1016/j.endonu.2013.04.006. Epub 2013 Aug 2.

Abstract

The impact of bariatric surgery beyond its effect on weight loss has entailed a change in the way of regarding it. The term metabolic surgery has become more popular to designate those interventions that aim at resolving diseases that have been traditionally considered as of exclusive medical management, such as type 2 diabetes mellitus (T2D). Recommendations for metabolic surgery have been largely addressed and discussed in worldwide meetings, but no definitive consensus has been reached yet. Rates of diabetes remission after metabolic surgery have been one of the most debated hot topics, with heterogeneity being a current concern. This review aims to identify and clarify controversies regarding metabolic surgery, by focusing on a critical analysis of T2D remission rates achieved with different bariatric procedures, and using different criteria for its definition. Indications for metabolic surgery for patients with T2D who are not morbidly obese are also discussed.

Keywords: Bariatric surgery; Cirugía bariátrica; Cirugía metabólica; Diabetes mellitus tipo 2; Metabolic surgery; Morbid obesity; Obesidad; Obesidad mórbida; Obesity; Remisión de la diabetes mellitus tipo 2; Review; Revisión; Type 2 diabetes mellitus; Type 2 diabetes mellitus remission.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Age Factors
  • Bariatric Surgery / methods
  • Bariatric Surgery / statistics & numerical data
  • Bariatric Surgery / trends*
  • C-Peptide / blood
  • Combined Modality Therapy
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / surgery
  • Diabetes Mellitus, Type 2 / therapy
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Male
  • Obesity, Morbid / surgery
  • Patient Selection
  • Prognosis
  • Remission Induction
  • Sex Factors
  • Treatment Outcome
  • Weight Loss

Substances

  • C-Peptide
  • Glycated Hemoglobin A