The present study examined the relationship between posttraumatic stress disorder (PTSD) and lateral preference, as reflected by handedness, in Israeli reserve combat troops. Data were gathered from 147 right-handed reserve combat personnel who filled out the Edinburgh Handedness Inventory, a questionnaire examining the severity of PTSD symptoms according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria and a questionnaire on the details of military service and familial status. The participants without children exhibited significantly more PTSD symptoms compared with the participants with children but did not differ in lateral preference levels. Multiple linear regression analysis revealed an altered pattern in the relationship between PTSD symptoms severity and lateral preference between the two groups. This alternation could suggest that being a parent might compel a reservist to inhibit the use of avoidance mechanisms for coping with intrusive memories, resulting in reduction of visible symptoms of PTSD while respectively contributing to their synchronization to lateral preference.