Evaluation of larvicidal activity and brine shrimp toxicity of rhizome extracts of Zingiber zerumbet (L.) Smith

Rev Soc Bras Med Trop. 2013 May-Jun;46(3):377-80. doi: 10.1590/0037-8682-1309-2013.

Abstract

Introduction: In this study, we used dichloromethane (DCM) and methanol (MeOH) extracts of the Zingiber zerumbet rhizome to evaluate brine shrimp lethality and larvicidal activity on Aedes aegypti and Anopheles nuneztovari mosquitoes.

Methods: Bioassays were performed by exposing third-instar larvae of each mosquito species to the DCM or MeOH extracts.

Results: Probit analysis with DCM and MeOH extracts demonstrated efficient larvicidal activity against A. aegypti and A. nuneztovari larvae.

Conclusions: The DCM and MeOH extracts showed higher activity against A. nuneztovari larvae than against A. aegypti larvae, suggesting that the extracts have species-specific activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aedes / drug effects*
  • Animals
  • Anopheles / drug effects*
  • Artemia / drug effects*
  • Biological Assay
  • Larva / drug effects
  • Methanol / isolation & purification
  • Methanol / pharmacology
  • Methylene Chloride / isolation & purification
  • Methylene Chloride / pharmacology
  • Plant Extracts / pharmacology*
  • Rhizome / chemistry*
  • Survival Analysis
  • Zingiberaceae / chemistry*

Substances

  • Plant Extracts
  • Methylene Chloride
  • Methanol