Stenting of the right ventricular outflow tract

Heart. 2013 Nov;99(21):1603-8. doi: 10.1136/heartjnl-2013-304155. Epub 2013 Jul 11.

Abstract

Objective: To assess the indication, technical aspects, and outcome of stenting of the right ventricular outflow tract (RVOT) in the management of symptomatic patients with severely limited pulmonary blood flow.

Methods: Retrospective case note and procedure review of patients undergoing stenting of the RVOT over an 8 year period.

Patients: Between 2005 and 2012, 52 selected patients underwent percutaneous stent implantation into a very narrow RVOT to improve pulmonary blood flow. Median age at stent implantation was 63 (range 4-406) days and median weight was 3.8 (1.7-12.2) kg.

Results: 52 patients underwent stent implantation. Median procedure time was 57 (24-260) min and fluoroscopy time 16 (5.5-73) min. There was one procedural death (1.9%) and one emergency surgery (1.9%). Saturations increased from 71% (52-83%) to 92% (81-100%) (p<0.001). Two patients required early shunts due to inadequate palliation and two died from non-cardiac causes. Sixteen further catheter interventions were undertaken (balloon in 7, further stent in 9). Twenty-nine patients underwent delayed surgery (complete repair in 26, palliative in 3) at a median of 172 (52-758) days post-stenting. Left pulmonary artery Z score increased from a pre-interventional value of -1.75 (-4.96 to 0.67) to a pre-surgical value of -0.55 (-4.12 to 1.97), (p<0.01). Median right pulmonary artery Z score increased from -2.63 (-7.70 to 0.89) to -0.75 (-6.69 to 1.18) (p<0.01) . Seventeen patients remain well palliated after a median of 122 (40-286) days.

Conclusions: Stenting of the RVOT is an effective treatment option in the initial management of selected patients with very reduced pulmonary blood flow.

MeSH terms

  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / instrumentation*
  • Child, Preschool
  • Coronary Angiography
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pulmonary Circulation
  • Recovery of Function
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome
  • Ventricular Outflow Obstruction / diagnosis
  • Ventricular Outflow Obstruction / mortality
  • Ventricular Outflow Obstruction / physiopathology
  • Ventricular Outflow Obstruction / therapy*