Abstract
A novel strategy for aromatic trifluoromethylation by converting aromatic amino group into CF3 group is reported herein. This method, which can be considered as trifluoromethylation variation of the classic Sandmeyer reaction, uses readily available aromatic amines as starting materials and is performed under mild conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Diazonium Compounds / chemistry*
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Hydrocarbons, Fluorinated / chemical synthesis*
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Hydrocarbons, Fluorinated / chemistry
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Methylation
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Molecular Structure
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Salts / chemistry
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Silver / chemistry*
Substances
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Diazonium Compounds
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Hydrocarbons, Fluorinated
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Salts
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Silver