Cerebellitis developing after tricyclic antidepressant poisoning

Am J Emerg Med. 2013 Sep;31(9):1419.e3-5. doi: 10.1016/j.ajem.2013.05.001. Epub 2013 Jun 28.

Abstract

Acute cerebellitis is a rare inflammatory disease involving the cerebellum and is characterized by acute compromise of cerebellar functions. It most frequently originates from infectious causes, although cases of cerebellitis associated with other causes have also been reported. This report discusses a case of cerebellitis developing in a 4-year-old girl who had to be intubated after accidental ingestion of tricyclic antidepressant. There are no previous reports of cerebellitis after tricyclic antidepressant. This case shows that cerebellitis can develop in patients with poisoning of this kind.

Publication types

  • Case Reports

MeSH terms

  • Amitriptyline / poisoning*
  • Antidepressive Agents, Tricyclic / poisoning*
  • Brain / diagnostic imaging
  • Cerebellar Diseases / chemically induced*
  • Cerebellar Diseases / diagnosis
  • Cerebellar Diseases / diagnostic imaging
  • Cerebellar Diseases / pathology
  • Child, Preschool
  • Drug Overdose / complications*
  • Drug Overdose / diagnosis
  • Emergency Service, Hospital
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Neuroimaging
  • Tomography, X-Ray Computed

Substances

  • Antidepressive Agents, Tricyclic
  • Amitriptyline