The diagnosis and management of Morton's neuroma: a literature review

Foot Ankle Spec. 2013 Aug;6(4):307-17. doi: 10.1177/1938640013493464. Epub 2013 Jun 27.

Abstract

Morton's neuroma is a common condition mainly affecting middle aged women, and there are many proposed etiological theories involving chronic repetitive trauma, ischemia, entrapment, and intermetatarsal bursitis. Incorrect terminology suggests that the underlying pathological process is a nerve tumor, although histological examination reveals the presence of inflammatory tissue-that is, perineural fibrosis. The common digital nerve and its branches in the third planter webspace are most commonly affected. Diagnosis is usually made through history taking and clinical examination but may be aided by ultrasonography and magnetic resonance imaging. Current nonoperative treatment strategies include shoe-wear modifications, custom made orthoses, and injections of local anesthetic agents, sclerosing agents, and steroids. Operative management options primarily involve either nerve decompression or neurectomy. We have reviewed the published literature to evaluate the outcomes of the available diagnostic modalities and treatment options and present an algorithm for clinical practice.

Keywords: Morton’s neuroma; forefoot; midfoot; pain management; peripheral neuropathy; toe.

Publication types

  • Review

MeSH terms

  • Decompression, Surgical
  • Diagnostic Imaging
  • Foot / pathology
  • Foot / surgery
  • Glucocorticoids / therapeutic use
  • Humans
  • Injections, Intralesional
  • Nerve Block
  • Neuroma / diagnosis*
  • Neuroma / therapy*
  • Orthopedic Procedures
  • Pain / drug therapy
  • Pain / etiology
  • Pain / surgery
  • Peripheral Nervous System Neoplasms / diagnosis*
  • Peripheral Nervous System Neoplasms / therapy*
  • Physical Examination

Substances

  • Glucocorticoids