Interleukin-17 in veterinary animal species and its role in various diseases: a review

Cytokine. 2013 Oct;64(1):11-7. doi: 10.1016/j.cyto.2013.06.002. Epub 2013 Jun 28.

Abstract

Interleukin 17 (IL-17) as one of the pro-inflammatory cytokines is a very important player in the immune response to many pathogens and seems to play a role also in certain chronic and autoimmune diseases. Many studies showing the importance of this cytokine were conducted on murine models and human patients. In recent years, some experiments with other animals in which interleukin-17 was measured were carried out. This review is focused on the findings that have been observed and described in important veterinary species of animals.

Keywords: Cattle; Horse; Inflammation; Interleukin-17; Swine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / veterinary*
  • Cattle
  • Female
  • Gastrointestinal Tract / immunology
  • Gastrointestinal Tract / metabolism
  • Gastrointestinal Tract / microbiology
  • Humans
  • Inflammation / immunology
  • Inflammation / veterinary*
  • Interleukin-17 / metabolism*
  • Joint Diseases / metabolism
  • Joint Diseases / veterinary
  • Lung Diseases / metabolism
  • Lung Diseases / microbiology
  • Lung Diseases / veterinary
  • Mammary Glands, Animal / metabolism

Substances

  • Interleukin-17