In recent years, accumulating more and more evidence demonstrating the programming effects of intrauterine development on the subsequent health of the individual. Intrauterine fetal hypotrophy is a consequence of the wide range of pathological processes in different periods of pregnancy. It is the second leading cause of perinatal death after prematurity. Newborns from similar pathological pregnancies are often leaked premature baby and/or small for gestational age (SGA). Premature baby children have not only complicated and postnatal adaptation problems in the neonatal period, but many diseases occurring in later life: 1. Disorders in postnatal growth. 2. Neurological and intellectual consequences of IUH in term children (hyperactivity disorders attention, impaired fine motor skills, speech problems, risk of cerebral palsy). 3. Neurological and intellectual consequences of prematurity IUH (cognitive impairment in children with low birth weight, short stature at birth, and small head circumference for gestational age). 4. Metabolic syndrome (dyslipidemia, abdominal obesity, hypertension and high blood sugar). 5. Abnormal sexual development (hyperandrogenism, polycystic ovary syndrome in girls, reduced testicular size and lower testosterone levels in boys. 6. Other complications associated with intrauterine hypotrophy cardiovascular renal, pulmonary complications (BPD) disorders in vision, sensory neural hearing loss.