Effect of physical activity on weight loss, energy expenditure, and energy intake during diet induced weight loss

Obesity (Silver Spring). 2014 Feb;22(2):363-70. doi: 10.1002/oby.20525. Epub 2013 Aug 23.

Abstract

Objective: Objective measurements of physical activity (PA), energy expenditure (EE) and energy intake can provide valuable information regarding appropriate strategies for successful sustained weight loss.

Design and methods: The total EE was examined by doubly labeled water, resting metabolic rate by indirect calorimetry, PA with activity monitors, and energy intake by the intake/balance technique in 116 severely obese undergoing intervention with diet alone (DO) or diet plus PA (D-PA).

Results: Weight loss of 9.6 ± 6.8 kg resulted in decreased EE which was not minimized in the D-PA group. Comparing the highest and lowest quartiles of increase in PA revealed a lower decrease in TDEE (-122 ± 319 vs. -376 ± 305 kcal day⁻¹), elimination of the drop in AEE (83 ± 279 vs. -211 ± 284 kcal day⁻¹) and greater weight loss (13.0 ± 7.0 vs. 8.1 ± 6.3 kg). Increased PA was associated with greater adherence to energy restriction and maintenance of greater weight loss during months 7-12.

Conclusion: Noncompliance to prescribed PA in the DO and D-PA groups partially masked the effects of PA to increase weight loss and to minimize the reduced EE. Increased PA was also associated with improved adherence to prescribed caloric restriction. A strong recommendation needs to be made to improve interventions that promote PA within the context of behavioral weight loss interventions.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adiposity
  • Adult
  • Behavior Therapy
  • Body Mass Index
  • Combined Modality Therapy
  • Diet, Reducing*
  • Energy Intake*
  • Energy Metabolism*
  • Fatty Liver / etiology
  • Fatty Liver / prevention & control
  • Female
  • Humans
  • Intra-Abdominal Fat / pathology
  • Liver / pathology
  • Male
  • Middle Aged
  • Monitoring, Ambulatory
  • Motor Activity*
  • Obesity, Morbid / metabolism
  • Obesity, Morbid / pathology
  • Obesity, Morbid / physiopathology
  • Obesity, Morbid / therapy*
  • Patient Compliance
  • Pennsylvania
  • Walking
  • Weight Loss*