We report a case of a 55 year-old female with chronic renal failure who received routine haemodialysis and suffered from acute myocardial infarction of inferior wall. Based on coronary angiogram, transoesophageal echocardiography, and autopsy,coronary embolisation with vegetations in the course of infective endocarditis was identified as a rare cause of ST-segment elevation myocardial infarction.