Synthesis and activity of a novel, irreversible inhibitor of cathepsin B

Biochem Soc Trans. 1990 Apr;18(2):315-6. doi: 10.1042/bst0180315.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Biotin / analogs & derivatives*
  • Biotin / chemical synthesis
  • Biotin / pharmacology
  • Cathepsin B / antagonists & inhibitors*
  • Cattle
  • Cysteine Proteinase Inhibitors / pharmacology
  • Diazomethane / analogs & derivatives*
  • Diazomethane / chemical synthesis
  • Diazomethane / pharmacology
  • In Vitro Techniques

Substances

  • Cysteine Proteinase Inhibitors
  • benzyloxycarbonylphenylalanylalanine diazomethyl ketone
  • biotin-phenylalanyl-alanine diazomethyl ketone
  • Diazomethane
  • Biotin
  • Cathepsin B