Rupatadine

Acta Crystallogr Sect E Struct Rep Online. 2013 May 31;69(Pt 6):o980. doi: 10.1107/S1600536813014256. Print 2013 Jun 1.

Abstract

8-chloro-11-{1-[(5-methyl-pyridin-3-yl)meth-yl]piperidin-4-yl-idene}-6,11-di-hydro-5H-benzo[5,6]cyclo-hepta-[1,2-b]pyridine), C26H26ClN3, the dihedral angle between the mean planes of the chloro-phenyl and cyclo-hepta-[1,2-b]pyridinyl rings fused to the cyclo-heptane ring is 56.6 (1)°. The mean planes of the cyclo-hepta-[1,2-b]pyridinyl and 5-methyl-pyridin-3-yl rings are twisted by 64.9 (4)°. The central piperizene group is in a slightly distorted chair configuration. A weak intra-molecular C-H⋯N inter-action is observed between the cyclo-hepta-[1,2-b]pyridinyl and piperidin-4-yl-idene moieties.