Substituent-guided switch between C-H activation and decarboxylative cross-coupling during palladium/copper-catalyzed cascade reactions of 2-aminobenzoates with 2-haloarylaldehydes

Chemistry. 2013 Aug 5;19(32):10487-91. doi: 10.1002/chem.201301705. Epub 2013 Jun 20.

Authors

Subhendu Bhowmik¹, Garima Pandey, Sanjay Batra

Affiliation

¹ Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, PO Box 173, Lucknow 226031, India.

PMID: 23788483
DOI: 10.1002/chem.201301705

No abstract available

Keywords: CH activation; copper; decarboxylative cross-coupling; nitrogen heterocycles; palladium.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry*
Carbon / chemistry
Catalysis
Copper / chemistry*
Decarboxylation
Hydrogen / chemistry
Indole Alkaloids / chemical synthesis
Indole Alkaloids / chemistry
Palladium / chemistry*
Phenanthridines / chemical synthesis
Phenanthridines / chemistry
Quinolines / chemical synthesis
Quinolines / chemistry
ortho-Aminobenzoates / chemistry*

Substances

Aldehydes
Indole Alkaloids
Phenanthridines
Quinolines
isocryptolepine
ortho-Aminobenzoates
Palladium
Carbon
Copper
Hydrogen