Abstract
Susceptibility breakpoints are crucial for prudent use of antimicrobials. This study has developed the first susceptibility breakpoint (MIC ≤ 0.25 μg/ml) for enrofloxacin against swine Salmonella spp. based on wild-type cutoff (COWT) and pharmacokinetic-pharmacodynamic (PK-PD) cutoff (COPD) values, consequently providing a criterion for susceptibility testing and clinical usage of enrofloxacin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology*
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Enrofloxacin
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Fluoroquinolones / pharmacology*
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Microbial Sensitivity Tests
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Salmonella / drug effects*
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Salmonella / isolation & purification
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Salmonella Infections, Animal / microbiology*
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Swine
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Swine Diseases / microbiology*
Substances
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Anti-Bacterial Agents
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Fluoroquinolones
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Enrofloxacin