Ultrasound parameters and L/S ratio in prediction of perinatal outcome in term-growth restricted newborns

Clin Exp Obstet Gynecol. 2013;40(1):113-5.

Abstract

Aim: The relation between biophysical profile (BPP), cerebroplacental (C/P) ratio, and lecithin/sphingomyelin (L/S) ratio as a predictor perinatal outcome in term intrauterine growth restricted (IUGR) neonates was evaluated.

Materials and methods: A retrospective study of the perinatal outcome of 77 term monofetal pregnancies complicated with IUGR fetuses (< 10 percentile) who were terminated by cesarean section in 2010 was performed at the Institute of Gynecology and Obstetrics, Belgrade.

Results: The most frequent early neonatal complication was asphyxia. The authors found a strong correlation between the L/S ratio and birth weight (BW) r = 0.609, as well as between BPP and Apgar score 5 r = 0.583. Significant negative correlation was found between asphyxia and BPP r = -0.398, as well as between asphyxia and C/P ratio r = -0.379.

Conclusion: In serous IUGR neonates, low values of BPP and L/S ratios predicted asphyxia.

MeSH terms

  • Adult
  • Asphyxia Neonatorum / diagnostic imaging*
  • Asphyxia Neonatorum / metabolism
  • Female
  • Fetal Growth Retardation / diagnostic imaging*
  • Fetal Growth Retardation / metabolism
  • Humans
  • Infant, Newborn
  • Lecithins / metabolism
  • Middle Cerebral Artery / diagnostic imaging
  • Placenta / diagnostic imaging
  • Predictive Value of Tests
  • Pregnancy
  • Respiratory Distress Syndrome, Newborn / diagnostic imaging*
  • Respiratory Distress Syndrome, Newborn / metabolism
  • Retrospective Studies
  • Sphingomyelins / metabolism
  • Ultrasonography, Prenatal
  • Umbilical Arteries / diagnostic imaging
  • Vascular Resistance
  • Young Adult

Substances

  • Lecithins
  • Sphingomyelins