Micropatterning hydrophobic liquid on a porous polymer surface for long-term selective cell-repellency

Adv Healthc Mater. 2013 Nov;2(11):1425-9. doi: 10.1002/adhm.201300073. Epub 2013 May 28.

Abstract

A simple method to form precise micropatterns of hydrophobic liquids using porous hydrophilic-hydrophobic substrates is presented. The micropatterns of hydrophobic liquid exhibit long-term stability, excellent cell-repellency, no cytotoxicity, and are more efficient than conventional PEG or superhydrophobic surfaces in controlling eukaryotic cell adhesion.

Keywords: cell repellent; liquid-liquid; micropatterns; porous polymers; slippery surfaces.

MeSH terms

  • Cells / cytology*
  • Cells / metabolism
  • Green Fluorescent Proteins / metabolism
  • HEK293 Cells
  • HeLa Cells
  • Humans
  • Hydrophobic and Hydrophilic Interactions*
  • Microtechnology / methods*
  • Polymers / chemistry*
  • Porosity
  • Surface Properties
  • Time Factors

Substances

  • Polymers
  • Green Fluorescent Proteins