Efficacy of antibiotic prophylaxis for preventing intrathoracic infections, after thoracostomy, for traumatic haemo/pneumothorax - experience of Oradea county emergency hospital

Rev Med Chir Soc Med Nat Iasi. 2012 Oct-Dec;116(4):1157-61.

Abstract

The aim of the paper is to observe the effectiveness of prophylactic administration of antibacterials against empyema and pneumonia after tube thoracostomy for traumatic collections.

Material and methods: Observational retrospective study over a ten years period (2002-2011), at the Oradea County Emergency Hospital on 939 patients with chest tube drainage for traumatic haemo/pneumothoraces. The morbidity by intrathoracic infections was 5,5% in the curative antibiotic group.

Results: The median number of risk factors for surgical infections and case severity were not statistically different (p=0.9653 and p=0,6601) between cases with antibioprophylaxis and curative treatment, but the incidence of intrathoracic infection in the prophylaxis group (n=86) was half (2,3%). Antibioprophylaxis was effective in over 95% of the cases and it associated in-hospital length of stay, length of stay in the ICU and costs of care significantly (p<0.0001, p<0.0001, p=0.0046) lesser than of those patients treated with curative regimen. The overall mortality was 8.6% within the curative regimen group with an attributable mortality to infections of 17.39%; but it was only 2.3% and respectively 0 within the prophylaxis group.

Conclusions: Antibiotic prophylaxis for intrathoracic infections after tube thoracostomy for traumatic collections was justified by case severity and risk factors and was effective and cost-efficient, but it should be administered selectively.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Chest Tubes / adverse effects
  • Emergency Service, Hospital
  • Empyema, Pleural / mortality
  • Empyema, Pleural / prevention & control*
  • Hemopneumothorax / drug therapy*
  • Hemopneumothorax / etiology
  • Hemopneumothorax / surgery*
  • Hospitals, County
  • Humans
  • Incidence
  • Length of Stay
  • Pneumonia, Bacterial / mortality
  • Pneumonia, Bacterial / prevention & control*
  • Retrospective Studies
  • Risk Factors
  • Romania / epidemiology
  • Thoracic Injuries / complications
  • Thoracic Injuries / surgery*
  • Thoracostomy* / adverse effects
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents