Abstract
A concise solid-phase synthesis of inverse poly(amidoamine) dendrons was developed. Upon introduction of AB2-type monomers, each dendron generation was constructed via one reaction. G2 to G5 dendrons were constructed in a peptide synthesizer in 93%, 89%, 82%, and 78% yields, respectively, within 5 days.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkylation
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Amines / chemistry
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Automation
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Carboxylic Acids / chemistry
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Dendrimers / chemical synthesis*
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Dendrimers / chemistry
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Polyamines / chemistry*
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Solid-Phase Synthesis Techniques
Substances
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Amines
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Carboxylic Acids
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Dendrimers
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Poly(amidoamine)
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Polyamines