The expression of TAM receptors and their ligand Gas6 is downregulated in psoriasis

J Dermatol Sci. 2013 Sep;71(3):215-6. doi: 10.1016/j.jdermsci.2013.04.018. Epub 2013 Apr 28.
No abstract available

Keywords: Negative regulation of innate immunity; Psoriasis; TAM receptors.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoimmunity / genetics
  • Down-Regulation
  • Humans
  • Intercellular Signaling Peptides and Proteins / genetics*
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Interleukin-6 / genetics
  • Interleukin-6 / metabolism
  • Ligands
  • Mice
  • Mice, Inbred BALB C
  • Psoriasis / etiology
  • Psoriasis / genetics*
  • Psoriasis / metabolism*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Receptor Protein-Tyrosine Kinases / genetics*
  • Receptor Protein-Tyrosine Kinases / metabolism*

Substances

  • IL6 protein, human
  • Intercellular Signaling Peptides and Proteins
  • Interleukin-6
  • Ligands
  • RNA, Messenger
  • growth arrest-specific protein 6
  • interleukin-6, mouse
  • Receptor Protein-Tyrosine Kinases