Chromatin remodeling, BRCA1, SAHF and cellular senescence

Cell Cycle. 2013 Jun 1;12(11):1653-4. doi: 10.4161/cc.24986. Epub 2013 May 10.
No abstract available

Keywords: BRCA1; BRG1; DNA damage response; oncogene-induced senescence; pRB; pericentromeric heterochromatin; senescence-associated heterochromatin foci (SAHF).

Publication types

  • Editorial

MeSH terms

  • BRCA1 Protein / antagonists & inhibitors
  • BRCA1 Protein / metabolism*
  • Cell Line
  • Cellular Senescence*
  • Chromatin Assembly and Disassembly
  • Cyclin-Dependent Kinase Inhibitor p16 / metabolism
  • Cyclin-Dependent Kinase Inhibitor p21 / metabolism
  • DNA Helicases / genetics
  • DNA Helicases / metabolism
  • Gene Silencing
  • Heterochromatin / metabolism*
  • Humans
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism
  • Retinoblastoma Protein / metabolism
  • Transcription Factors / genetics
  • Transcription Factors / metabolism
  • Up-Regulation

Substances

  • BRCA1 Protein
  • Cyclin-Dependent Kinase Inhibitor p16
  • Cyclin-Dependent Kinase Inhibitor p21
  • Heterochromatin
  • Nuclear Proteins
  • Retinoblastoma Protein
  • Transcription Factors
  • SMARCA4 protein, human
  • DNA Helicases