Technical aspects of intestinal transplantation

Curr Opin Organ Transplant. 2013 Jun;18(3):291-7. doi: 10.1097/MOT.0b013e3283615da1.

Abstract

Purpose of review: Intestinal transplantation includes an heterogeneous group of procedures in which different compositions of organs are transplanted. The current classification includes four groups according to the inclusion of the liver and/or the stomach in the graft: isolated intestinal transplantation, liver-intestinal transplantation, multivisceral transplantation, and modified multivisceral transplantation. Variants exist, the technical evolution having been slow, yet constant over years.

Recent findings: The most relevant early technical improvements were aimed at achieving better feasibility and safety of the most difficult aspects of the different procedures, such as removal of the recipient's diseased organs, performing of vascular reconstructions and prevention of complications as with retention of the donor's duodenum and pancreas in liver-intestine transplantation. More recently, apart from a clear definition of the classification of the procedures, progress has been more directed in a conservative direction such as the preservation of the native spleen with and without the pancreas in multivisceral transplants.

Summary: After achieving consistent satisfactory short-term results, the technical interest in intestinal transplantation is now moved to solutions that, in spite of a possible increased difficulty, may offer better opportunities of mid-term and long-term successes, both in terms of survival and quality of life.

Publication types

  • Review

MeSH terms

  • Digestive System Surgical Procedures / methods*
  • Humans
  • Intestines / transplantation*
  • Liver Transplantation*
  • Pancreas Transplantation*
  • Plastic Surgery Procedures*
  • Stomach / transplantation*