Abstract
Three recently published reports, including one in Cell Research, generated Ssb1 knockout mice and demonstrated critical roles of this protein in regulating skeletogenesis, telomere homeostasis and tumor suppression.
MeSH terms
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Animals
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Ataxia Telangiectasia Mutated Proteins / metabolism
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Cell Line
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DNA Repair
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Humans
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Mice
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Mice, Knockout
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RNA Interference
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RNA, Small Interfering
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Suppressor of Cytokine Signaling Proteins / genetics
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Suppressor of Cytokine Signaling Proteins / metabolism*
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Telomere Homeostasis / physiology*
Substances
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RNA, Small Interfering
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SSB-1 protein, mouse
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Suppressor of Cytokine Signaling Proteins
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Ataxia Telangiectasia Mutated Proteins
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Atm protein, mouse